Several British kings went mad as a result of a blood disorder that causes gout and mental derangement. The most famous was Mad George III, who ruled England in the 18th Century. George was afflicted with porphyria, a maddening disease which disrupted his reign as early as 1765. Several attacks strained his grip on reality and debilitated him in the last years of his reign. Keeping it in the family, in 1776 his sister, Princess Caroline Mathilda married, at age 15, the deranged Christian VII of Denmark. George III died blind, deaf and mad at Windsor Castle on January, 29 1820. The United States briefly enjoyed the services of a monarch, Emperor Norton I, who proclaimed himself Emperor of the United States and Protector of Mexico in 1859. He had all his “state proclamations” published in San Francisco’s newspapers and wrote letters that were seriously considered by Abraham Lincoln and Queen Victoria.